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A novel role for poly(C) binding proteins in programmed ribosomal frameshifting

Translational control through programmed ribosomal frameshifting (PRF) is exploited widely by viruses and increasingly documented in cellular genes. Frameshifting is induced by mRNA secondary structures that compromise ribosome fidelity during decoding of a heptanucleotide ‘slippery’ sequence. The n...

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Detalles Bibliográficos
Autores principales: Napthine, Sawsan, Treffers, Emmely E., Bell, Susanne, Goodfellow, Ian, Fang, Ying, Firth, Andrew E., Snijder, Eric J., Brierley, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937337/
https://www.ncbi.nlm.nih.gov/pubmed/27257056
http://dx.doi.org/10.1093/nar/gkw480