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Ribosome recycling defects modify the balance between the synthesis and assembly of specific subunits of the oxidative phosphorylation complexes in yeast mitochondria

Mitochondria have their own translation machinery that produces key subunits of the OXPHOS complexes. This machinery relies on the coordinated action of nuclear-encoded factors of bacterial origin that are well conserved between humans and yeast. In humans, mutations in these factors can cause disea...

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Detalles Bibliográficos
Autores principales: Ostojić, Jelena, Panozzo, Cristina, Bourand-Plantefol, Alexa, Herbert, Christopher J., Dujardin, Geneviève, Bonnefoy, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937339/
https://www.ncbi.nlm.nih.gov/pubmed/27257059
http://dx.doi.org/10.1093/nar/gkw490