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Ribosome recycling defects modify the balance between the synthesis and assembly of specific subunits of the oxidative phosphorylation complexes in yeast mitochondria
Mitochondria have their own translation machinery that produces key subunits of the OXPHOS complexes. This machinery relies on the coordinated action of nuclear-encoded factors of bacterial origin that are well conserved between humans and yeast. In humans, mutations in these factors can cause disea...
Autores principales: | Ostojić, Jelena, Panozzo, Cristina, Bourand-Plantefol, Alexa, Herbert, Christopher J., Dujardin, Geneviève, Bonnefoy, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937339/ https://www.ncbi.nlm.nih.gov/pubmed/27257059 http://dx.doi.org/10.1093/nar/gkw490 |
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