The human PMR1 endonuclease stimulates cell motility by down regulating miR-200 family microRNAs

The motility of MCF-7 cells increases following expression of a human PMR1 transgene and the current study sought to identify the molecular basis for this phenotypic change. Ensemble and single cell analyses show increased motility is dependent on the endonuclease activity of hPMR1, and cells expres...

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Detalles Bibliográficos
Autores principales: Gu, Shan-Qing, Gallego-Perez, Daniel, McClory, Sean P., Shi, Junfeng, Han, Joonhee, Lee, L. James, Schoenberg, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937341/
https://www.ncbi.nlm.nih.gov/pubmed/27257068
http://dx.doi.org/10.1093/nar/gkw497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937341/
https://www.ncbi.nlm.nih.gov/pubmed/27257068
http://dx.doi.org/10.1093/nar/gkw497

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