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Entropy gives rise to topologically associating domains

We investigate chromosome organization within the nucleus using polymer models whose formulation is closely guided by experiments in live yeast cells. We employ bead-spring chromosome models together with loop formation within the chains and the presence of nuclear bodies to quantify the extent to w...

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Detalles Bibliográficos
Autores principales: Vasquez, Paula A., Hult, Caitlin, Adalsteinsson, David, Lawrimore, Josh, Forest, Mark G., Bloom, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937343/
https://www.ncbi.nlm.nih.gov/pubmed/27257057
http://dx.doi.org/10.1093/nar/gkw510