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Entropy gives rise to topologically associating domains
We investigate chromosome organization within the nucleus using polymer models whose formulation is closely guided by experiments in live yeast cells. We employ bead-spring chromosome models together with loop formation within the chains and the presence of nuclear bodies to quantify the extent to w...
Autores principales: | Vasquez, Paula A., Hult, Caitlin, Adalsteinsson, David, Lawrimore, Josh, Forest, Mark G., Bloom, Kerry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937343/ https://www.ncbi.nlm.nih.gov/pubmed/27257057 http://dx.doi.org/10.1093/nar/gkw510 |
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