Methotrexate Nanoparticles Prepared with Codendrimer from Polyamidoamine (PAMAM) and Oligoethylene Glycols (OEG) Dendrons: Antitumor Efficacy in Vitro and in Vivo

The novel methotrexate-loaded nanoparticles (MTX/PGD NPs) prepared with amphiphilic codendrimer PGD from polyamidoamine and oligothylene glycol dendrons were obtained via antisolvent precipitation method augmented by ultrasonication. Based on the excellent hydrophility of PGD, the drug-loaded nanopa...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Yanna, Guo, Yifei, Li, Ran, Wang, Ting, Han, Meihua, Zhu, Chunyan, Wang, Xiangtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937365/
https://www.ncbi.nlm.nih.gov/pubmed/27388443
http://dx.doi.org/10.1038/srep28983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937365/
https://www.ncbi.nlm.nih.gov/pubmed/27388443
http://dx.doi.org/10.1038/srep28983

Ejemplares similares