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TMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influenza A Virus
Influenza A and B viruses show clear differences in their host specificity and pandemic potential. Recent studies have revealed that the host protease TMPRSS2 plays an essential role for proteolytic activation of H1, H3, and H7 subtype strains of influenza A virus (IAV) in vivo. IAV possessing a mon...
Autores principales: | Sakai, Kouji, Ami, Yasushi, Nakajima, Noriko, Nakajima, Katsuhiro, Kitazawa, Minori, Anraku, Masaki, Takayama, Ikuyo, Sangsriratanakul, Natthanan, Komura, Miyuki, Sato, Yuko, Asanuma, Hideki, Takashita, Emi, Komase, Katsuhiro, Takehara, Kazuaki, Tashiro, Masato, Hasegawa, Hideki, Odagiri, Takato, Takeda, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937385/ https://www.ncbi.nlm.nih.gov/pubmed/27389476 http://dx.doi.org/10.1038/srep29430 |
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