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Effects of Water on Structure and Dynamics of Trehalose Glasses at Low Water Contents and its Relationship to Preservation Outcomes

Dry preservation of biologics in sugar glasses is regarded as a promising alternative to conventional cryopreservation. Evidence from various studies has suggested that there is a critical range of water content beyond which the viability of preserved biologics can be greatly compromised. In this st...

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Detalles Bibliográficos
Autores principales: Weng, Lindong, Ziaei, Shima, Elliott, Gloria D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937400/
https://www.ncbi.nlm.nih.gov/pubmed/27387435
http://dx.doi.org/10.1038/srep28795