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Peroxiredoxin 1 interacts with and blocks the redox factor APE1 from activating interleukin-8 expression
APE1 is an essential DNA repair protein that also possesses the ability to regulate transcription. It has a unique cysteine residue C65, which maintains the reduce state of several transcriptional activators such as NF-κB. How APE1 is being recruited to execute the various biological functions remai...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937415/ https://www.ncbi.nlm.nih.gov/pubmed/27388124 http://dx.doi.org/10.1038/srep29389 |