Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus

Hepatitis B virus (HBV) is not eradicated by current antiviral therapies due to persistence of HBV covalently closed circular DNA (cccDNA) in host cells, and thus development of novel culture models for productive HBV infection is urgently needed, which will allow the study of HBV cccDNA eradication...

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Detalles Bibliográficos
Autores principales: Kaneko, Shun, Kakinuma, Sei, Asahina, Yasuhiro, Kamiya, Akihide, Miyoshi, Masato, Tsunoda, Tomoyuki, Nitta, Sayuri, Asano, Yu, Nagata, Hiroko, Otani, Satoshi, Kawai-Kitahata, Fukiko, Murakawa, Miyako, Itsui, Yasuhiro, Nakagawa, Mina, Azuma, Seishin, Nakauchi, Hiromitsu, Nishitsuji, Hironori, Ujino, Saneyuki, Shimotohno, Kunitada, Iwamoto, Masashi, Watashi, Koichi, Wakita, Takaji, Watanabe, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937433/
https://www.ncbi.nlm.nih.gov/pubmed/27386799
http://dx.doi.org/10.1038/srep29358

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