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Glucose and Palmitate Differentially Regulate PFKFB3/iPFK2 and Inflammatory Responses in Mouse Intestinal Epithelial Cells
The gene PFKFB3 encodes for inducible 6-phosphofructo-2-kinase, a glycolysis-regulatory enzyme that protects against diet-induced intestine inflammation. However, it is unclear how nutrient overload regulates PFKFB3 expression and inflammatory responses in intestinal epithelial cells (IECs). In the...
Autores principales: | Botchlett, Rachel, Li, Honggui, Guo, Xin, Qi, Ting, Zhao, JiaJia, Zheng, Juan, Woo, Shih-Lung, Pei, Ya, Liu, Mengyang, Hu, Xiang, Chen, Guang, Guo, Ting, Yang, Sijun, Li, Qifu, Xiao, Xiaoqiu, Huo, Yuqing, Wu, Chaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937440/ https://www.ncbi.nlm.nih.gov/pubmed/27387960 http://dx.doi.org/10.1038/srep28963 |
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