Elevated variant density around SV breakpoints in germline lineage lends support to error-prone replication hypothesis

Copy number variants (CNVs) are a class of structural variants that may involve complex genomic rearrangements (CGRs) and are hypothesized to have additional mutations around their breakpoints. Understanding the mechanisms underlying CNV formation is fundamental for understanding the repair and muta...

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Detalles Bibliográficos
Autores principales: Dhokarh, Dhananjay, Abyzov, Alexej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937565/
https://www.ncbi.nlm.nih.gov/pubmed/27216746
http://dx.doi.org/10.1101/gr.205484.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937565/
https://www.ncbi.nlm.nih.gov/pubmed/27216746
http://dx.doi.org/10.1101/gr.205484.116

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