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Distinct transcription factor complexes act on a permissive chromatin landscape to establish regionalized gene expression in CNS stem cells

Spatially distinct gene expression profiles in neural stem cells (NSCs) are a prerequisite to the formation of neuronal diversity, but how these arise from the regulatory interactions between chromatin accessibility and transcription factor activity has remained unclear. Here, we demonstrate that, d...

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Detalles Bibliográficos
Autores principales: Hagey, Daniel W., Zaouter, Cécile, Combeau, Gaëlle, Lendahl, Monika Andersson, Andersson, Olov, Huss, Mikael, Muhr, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937566/
https://www.ncbi.nlm.nih.gov/pubmed/27197220
http://dx.doi.org/10.1101/gr.203513.115