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Basset: learning the regulatory code of the accessible genome with deep convolutional neural networks
The complex language of eukaryotic gene expression remains incompletely understood. Despite the importance suggested by many noncoding variants statistically associated with human disease, nearly all such variants have unknown mechanisms. Here, we address this challenge using an approach based on a...
Autores principales: | Kelley, David R., Snoek, Jasper, Rinn, John L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937568/ https://www.ncbi.nlm.nih.gov/pubmed/27197224 http://dx.doi.org/10.1101/gr.200535.115 |
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