Occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: a case report

BACKGROUND: Immunosuppressive therapy has been—until the recent release of new guidelines on diagnosis and management—the recommended treatment for idiopathic pulmonary fibrosis. However, its efficacy in patients with idiopathic pulmonary fibrosis has always been a matter of debate. CASE PRESENTATIO...

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Detalles Bibliográficos
Autores principales: Cerri, Stefania, Sgalla, Giacomo, Richeldi, Luca, Luppi, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937572/
https://www.ncbi.nlm.nih.gov/pubmed/27387033
http://dx.doi.org/10.1186/s13256-016-0916-5
Descripción
Sumario:BACKGROUND: Immunosuppressive therapy has been—until the recent release of new guidelines on diagnosis and management—the recommended treatment for idiopathic pulmonary fibrosis. However, its efficacy in patients with idiopathic pulmonary fibrosis has always been a matter of debate. CASE PRESENTATION: We report the occurrence of idiopathic pulmonary fibrosis in a white man receiving chronic immunosuppressive treatment following a heart transplant. CONCLUSIONS: This case report suggests that the immune mechanisms targeted by azathioprine and cyclosporine do not play a role in the pathogenesis of idiopathic pulmonary fibrosis.

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