Occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: a case report

BACKGROUND: Immunosuppressive therapy has been—until the recent release of new guidelines on diagnosis and management—the recommended treatment for idiopathic pulmonary fibrosis. However, its efficacy in patients with idiopathic pulmonary fibrosis has always been a matter of debate. CASE PRESENTATIO...

Descripción completa

Detalles Bibliográficos
Autores principales: Cerri, Stefania, Sgalla, Giacomo, Richeldi, Luca, Luppi, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937572/
https://www.ncbi.nlm.nih.gov/pubmed/27387033
http://dx.doi.org/10.1186/s13256-016-0916-5
_version_ 1782441731079274496
author Cerri, Stefania
Sgalla, Giacomo
Richeldi, Luca
Luppi, Fabrizio
author_facet Cerri, Stefania
Sgalla, Giacomo
Richeldi, Luca
Luppi, Fabrizio
author_sort Cerri, Stefania
collection PubMed
description BACKGROUND: Immunosuppressive therapy has been—until the recent release of new guidelines on diagnosis and management—the recommended treatment for idiopathic pulmonary fibrosis. However, its efficacy in patients with idiopathic pulmonary fibrosis has always been a matter of debate. CASE PRESENTATION: We report the occurrence of idiopathic pulmonary fibrosis in a white man receiving chronic immunosuppressive treatment following a heart transplant. CONCLUSIONS: This case report suggests that the immune mechanisms targeted by azathioprine and cyclosporine do not play a role in the pathogenesis of idiopathic pulmonary fibrosis.
format Online
Article
Text
id pubmed-4937572
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-49375722016-07-09 Occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: a case report Cerri, Stefania Sgalla, Giacomo Richeldi, Luca Luppi, Fabrizio J Med Case Rep Case Report BACKGROUND: Immunosuppressive therapy has been—until the recent release of new guidelines on diagnosis and management—the recommended treatment for idiopathic pulmonary fibrosis. However, its efficacy in patients with idiopathic pulmonary fibrosis has always been a matter of debate. CASE PRESENTATION: We report the occurrence of idiopathic pulmonary fibrosis in a white man receiving chronic immunosuppressive treatment following a heart transplant. CONCLUSIONS: This case report suggests that the immune mechanisms targeted by azathioprine and cyclosporine do not play a role in the pathogenesis of idiopathic pulmonary fibrosis. BioMed Central 2016-05-25 /pmc/articles/PMC4937572/ /pubmed/27387033 http://dx.doi.org/10.1186/s13256-016-0916-5 Text en © Cerri et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Cerri, Stefania
Sgalla, Giacomo
Richeldi, Luca
Luppi, Fabrizio
Occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: a case report
title Occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: a case report
title_full Occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: a case report
title_fullStr Occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: a case report
title_full_unstemmed Occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: a case report
title_short Occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: a case report
title_sort occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937572/
https://www.ncbi.nlm.nih.gov/pubmed/27387033
http://dx.doi.org/10.1186/s13256-016-0916-5
work_keys_str_mv AT cerristefania occurrenceofidiopathicpulmonaryfibrosisduringimmunosuppressivetreatmentacasereport
AT sgallagiacomo occurrenceofidiopathicpulmonaryfibrosisduringimmunosuppressivetreatmentacasereport
AT richeldiluca occurrenceofidiopathicpulmonaryfibrosisduringimmunosuppressivetreatmentacasereport
AT luppifabrizio occurrenceofidiopathicpulmonaryfibrosisduringimmunosuppressivetreatmentacasereport

Ejemplares similares