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Early changes in the metabolic profile of activated CD8(+) T cells

BACKGROUND: Antigenic stimulation of the T cell receptor (TCR) initiates a change from a resting state into an activated one, which ultimately results in proliferation and the acquisition of effector functions. To accomplish this task, T cells require dramatic changes in metabolism. Therefore, we in...

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Detalles Bibliográficos
Autores principales: Cammann, Clemens, Rath, Alexander, Reichl, Udo, Lingel, Holger, Brunner-Weinzierl, Monika, Simeoni, Luca, Schraven, Burkhart, Lindquist, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937576/
https://www.ncbi.nlm.nih.gov/pubmed/27387758
http://dx.doi.org/10.1186/s12860-016-0104-x