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Micron-sized and submicron-sized aerosol deposition in a new ex vivo preclinical model
BACKGROUND: The knowledge of where particles deposit in the respiratory tract is crucial for understanding the health effects associated with inhaled drug particles. METHOD: An ex vivo study was conducted to assess regional deposition patterns (thoracic vs. extrathoracic) of radioactive polydisperse...
Autores principales: | Perinel, Sophie, Leclerc, Lara, Prévôt, Nathalie, Deville, Agathe, Cottier, Michèle, Durand, Marc, Vergnon, Jean-Michel, Pourchez, Jérémie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937580/ https://www.ncbi.nlm.nih.gov/pubmed/27388488 http://dx.doi.org/10.1186/s12931-016-0395-7 |
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