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Human mesenchymal stromal/stem cells acquire immunostimulatory capacity upon cross-talk with natural killer cells and might improve the NK cell function of immunocompromised patients

BACKGROUND: The suppressive effect of mesenchymal stromal/stem cells (MSCs) on diverse immune cells is well known, but it is unclear whether MSCs additionally possess immunostimulatory properties. We investigated the impact of human MSCs on the responsiveness of primary natural killer (NK) cells in...

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Detalles Bibliográficos
Autores principales:	Cui, Rongtao, Rekasi, Heike, Hepner-Schefczyk, Monika, Fessmann, Kai, Petri, Robert M., Bruderek, Kirsten, Brandau, Sven, Jäger, Marcus, Flohé, Stefanie B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937587/ https://www.ncbi.nlm.nih.gov/pubmed/27388156 http://dx.doi.org/10.1186/s13287-016-0353-9

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