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Pharmacodynamic evaluation of intragastric pH and implications for famotidine dosing in the prophylaxis of non-steroidal anti-inflammatory drug induced gastropathy—a proof of concept analysis

OBJECTIVE: Famotidine given at a dose of 80 mg/day is effective in preventing NSAID-induced gastropathy. The aim of this proof of concept study was to compare twice a day (BID) vs 3-times a day (TID) administration of this total dose of famotidine on intragastric pH in healthy volunteers. RESEARCH D...

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Detalles Bibliográficos
Autores principales:	Kent, Jeffery D., Holt, Robert J., Jung, Donald, Tidmarsh, George F., Grahn, Amy Y., Ball, Julie, Peura, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2014
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937634/ https://www.ncbi.nlm.nih.gov/pubmed/27536450 http://dx.doi.org/10.3109/21556660.2014.895371

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