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Sensing of Porcine Reproductive and Respiratory Syndrome Virus-Infected Macrophages by Plasmacytoid Dendritic Cells
Porcine reproductive and respiratory syndrome virus (PRRSV) represents a macrophage (MØ)-tropic virus which is unable to induce interferon (IFN) type I in its target cells. Nevertheless, infected pigs show a short but prominent systemic IFN alpha (IFN-α) response. A possible explanation for this dis...
Autores principales: | García-Nicolás, Obdulio, Auray, Gaël, Sautter, Carmen A., Rappe, Julie C. F., McCullough, Kenneth C., Ruggli, Nicolas, Summerfield, Artur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937788/ https://www.ncbi.nlm.nih.gov/pubmed/27458429 http://dx.doi.org/10.3389/fmicb.2016.00771 |
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