Effects of Developmental Activation of the Aryl Hydrocarbon Receptor by 2,3,7,8-Tetrachlorodibenzo-p-dioxin on Long-term Self-renewal of Murine Hematopoietic Stem Cells

BACKGROUND: Human epidemiological and animal studies suggest that developmental exposure to contaminants that activate the aryl hydrocarbon receptor (AHR) lead to suppression of immune system function throughout life. The persistence of immune deficiency throughout life suggests that the cellular ta...

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Detalles Bibliográficos
Autores principales: Laiosa, Michael D., Tate, Everett R., Ahrenhoerster, Lori S., Chen, Yuhong, Wang, Demin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937855/
https://www.ncbi.nlm.nih.gov/pubmed/26495820
http://dx.doi.org/10.1289/ehp.1509820

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