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CYP2C19 loss-of-function alleles are not associated with clinical outcome of clopidogrel therapy in patients treated with newer-generation drug-eluting stents

CYP2C19 loss-of-function (LOF) alleles adversely affect clinical outcome of clopidogrel therapy. Recent introduction of a newer-generation drug-eluting stent (DES) has significantly reduced the occurrence of stent thrombosis. The aim of this study was to evaluate the impact of CYP2C19 LOF alleles on...

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Detalles Bibliográficos
Autores principales: Choi, Ik Jun, Koh, Yoon-Seok, Park, Mahn-Won, Her, Sung Ho, Choi, Yun-Seok, Park, Chul-Soo, Park, Hun-Jun, Kim, Pum-Joon, Chung, Wook-Sung, Kim, Ho-Sook, Shin, Jae-Gook, Seung, Ki-Bae, Chang, Kiyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937952/
https://www.ncbi.nlm.nih.gov/pubmed/27368038
http://dx.doi.org/10.1097/MD.0000000000004049

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