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Calcium and adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2

Exocytotic secretion of digestive enzymes from pancreatic acinar cells is elicited by physiological cytosolic Ca(2+) signals, occurring as repetitive short-lasting spikes largely confined to the secretory granule region, that stimulate mitochondrial adenosine triphosphate (ATP) production. By contra...

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Detalles Bibliográficos
Autores principales:	Peng, Shuang, Gerasimenko, Julia V., Tsugorka, Tatiana, Gryshchenko, Oleksiy, Samarasinghe, Sujith, Petersen, Ole H., Gerasimenko, Oleg V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938023/ https://www.ncbi.nlm.nih.gov/pubmed/27377732 http://dx.doi.org/10.1098/rstb.2015.0423

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