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A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period

Topical corticosteroids (TCS) are regarded as the mainstay treatment for atopic dermatitis (AD). As AD has a tendency to heal naturally, the long-term efficacy of TCS in AD management should be compared with the outcomes seen in patients with AD not using TCS. However, there are few long-term studie...

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Autores principales: Fukaya, Mototsugu, Sato, Kenji, Yamada, Takahiro, Sato, Mitsuko, Fujisawa, Shigeki, Minaguchi, Satoko, Kimata, Hajime, Dozono, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938118/
https://www.ncbi.nlm.nih.gov/pubmed/27445501
http://dx.doi.org/10.2147/CCID.S109946
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author Fukaya, Mototsugu
Sato, Kenji
Yamada, Takahiro
Sato, Mitsuko
Fujisawa, Shigeki
Minaguchi, Satoko
Kimata, Hajime
Dozono, Haruhiko
author_facet Fukaya, Mototsugu
Sato, Kenji
Yamada, Takahiro
Sato, Mitsuko
Fujisawa, Shigeki
Minaguchi, Satoko
Kimata, Hajime
Dozono, Haruhiko
author_sort Fukaya, Mototsugu
collection PubMed
description Topical corticosteroids (TCS) are regarded as the mainstay treatment for atopic dermatitis (AD). As AD has a tendency to heal naturally, the long-term efficacy of TCS in AD management should be compared with the outcomes seen in patients with AD not using TCS. However, there are few long-term studies that consider patients with AD not using TCS. We designed a prospective multicenter cohort study to assess the clinical outcomes in patients with AD who did not use TCS for 6 months and then compared our results with an earlier study by Furue et al which considered AD patients using TCS over 6 months. Our patients’ clinical improvement was comparable with the patients described in Furue’s research. In light of this, it is reasonable for physicians to manage AD patients who decline TCS, as the expected long-term prognosis is similar whether they use TCS or not.
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spelling pubmed-49381182016-07-21 A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period Fukaya, Mototsugu Sato, Kenji Yamada, Takahiro Sato, Mitsuko Fujisawa, Shigeki Minaguchi, Satoko Kimata, Hajime Dozono, Haruhiko Clin Cosmet Investig Dermatol Original Research Topical corticosteroids (TCS) are regarded as the mainstay treatment for atopic dermatitis (AD). As AD has a tendency to heal naturally, the long-term efficacy of TCS in AD management should be compared with the outcomes seen in patients with AD not using TCS. However, there are few long-term studies that consider patients with AD not using TCS. We designed a prospective multicenter cohort study to assess the clinical outcomes in patients with AD who did not use TCS for 6 months and then compared our results with an earlier study by Furue et al which considered AD patients using TCS over 6 months. Our patients’ clinical improvement was comparable with the patients described in Furue’s research. In light of this, it is reasonable for physicians to manage AD patients who decline TCS, as the expected long-term prognosis is similar whether they use TCS or not. Dove Medical Press 2016-07-04 /pmc/articles/PMC4938118/ /pubmed/27445501 http://dx.doi.org/10.2147/CCID.S109946 Text en © 2016 Fukaya et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Fukaya, Mototsugu
Sato, Kenji
Yamada, Takahiro
Sato, Mitsuko
Fujisawa, Shigeki
Minaguchi, Satoko
Kimata, Hajime
Dozono, Haruhiko
A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period
title A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period
title_full A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period
title_fullStr A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period
title_full_unstemmed A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period
title_short A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period
title_sort prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938118/
https://www.ncbi.nlm.nih.gov/pubmed/27445501
http://dx.doi.org/10.2147/CCID.S109946
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