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Rapid Kinetics of Dehalogenation Promoted by Iodotyrosine Deiodinase from Human Thyroid

[Image: see text] Reductive dehalogenation such as that catalyzed by iodotyrosine deiodinase (IYD) is highly unusual in aerobic organisms but necessary for iodide salvage from iodotyrosine generated during thyroxine biosynthesis. Equally unusual is the dependence of this process on flavin. Rapid kin...

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Detalles Bibliográficos
Autores principales: Bobyk, Kostyantyn D., Ballou, David P., Rokita, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938124/
https://www.ncbi.nlm.nih.gov/pubmed/26151430
http://dx.doi.org/10.1021/acs.biochem.5b00410