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Rapid Kinetics of Dehalogenation Promoted by Iodotyrosine Deiodinase from Human Thyroid
[Image: see text] Reductive dehalogenation such as that catalyzed by iodotyrosine deiodinase (IYD) is highly unusual in aerobic organisms but necessary for iodide salvage from iodotyrosine generated during thyroxine biosynthesis. Equally unusual is the dependence of this process on flavin. Rapid kin...
Autores principales: | Bobyk, Kostyantyn D., Ballou, David P., Rokita, Steven E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938124/ https://www.ncbi.nlm.nih.gov/pubmed/26151430 http://dx.doi.org/10.1021/acs.biochem.5b00410 |
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