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Functional Characterization of the Osteoarthritis Susceptibility Mapping to CHST11—A Bioinformatics and Molecular Study

The single nucleotide polymorphism (SNP) rs835487 is associated with hip osteoarthritis (OA) at the genome-wide significance level and is located within CHST11, which codes for carbohydrate sulfotransferase 11. This enzyme post-translationally modifies proteoglycan prior to its deposition in the car...

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Detalles Bibliográficos
Autores principales:	Reynard, Louise N., Ratnayake, Madhushika, Santibanez-Koref, Mauro, Loughlin, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938163/ https://www.ncbi.nlm.nih.gov/pubmed/27391021 http://dx.doi.org/10.1371/journal.pone.0159024

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