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Calcium-Oxidant Signaling Network Regulates AMP-activated Protein Kinase (AMPK) Activation upon Matrix Deprivation

The AMP-activated protein kinase (AMPK) has recently been implicated in anoikis resistance. However, the molecular mechanisms that activate AMPK upon matrix detachment remain unexplored. In this study, we show that AMPK activation is a rapid and sustained phenomenon upon matrix deprivation, whereas...

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Detalles Bibliográficos
Autores principales: Sundararaman, Ananthalakshmy, Amirtham, Usha, Rangarajan, Annapoorni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938166/
https://www.ncbi.nlm.nih.gov/pubmed/27226623
http://dx.doi.org/10.1074/jbc.M116.731257