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Incidence, clinical manifestations and clipping of nail psoriasis in the dermatology center of the Hospital Universitário Evangélico de Curitiba

BACKGROUND: Psoriasis is a chronic inflammatory skin disease that often progresses with nail alterations. It is suspected that there is a correlation between nail psoriasis and enthesitis of the distal interphalangeal joint, seeming to serve as a predictor. OBJECTIVES: To analyze the profile of pati...

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Autores principales: Garbers, Luiz Eduardo Fabricio de Melo, Slongo, Helena, Fabricio, Lincoln Helder Zambaldi, Schmitt, Juliano Vilaverde, Bonalumi Filho, Aguinaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938273/
https://www.ncbi.nlm.nih.gov/pubmed/27438196
http://dx.doi.org/10.1590/abd1806-4841.20164296
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author Garbers, Luiz Eduardo Fabricio de Melo
Slongo, Helena
Fabricio, Lincoln Helder Zambaldi
Schmitt, Juliano Vilaverde
Bonalumi Filho, Aguinaldo
author_facet Garbers, Luiz Eduardo Fabricio de Melo
Slongo, Helena
Fabricio, Lincoln Helder Zambaldi
Schmitt, Juliano Vilaverde
Bonalumi Filho, Aguinaldo
author_sort Garbers, Luiz Eduardo Fabricio de Melo
collection PubMed
description BACKGROUND: Psoriasis is a chronic inflammatory skin disease that often progresses with nail alterations. It is suspected that there is a correlation between nail psoriasis and enthesitis of the distal interphalangeal joint, seeming to serve as a predictor. OBJECTIVES: To analyze the profile of patients with nail psoriasis and correlate the presence of nail alterations with psoriatic arthritis, quality of life, extent of psoriasis and the histopathology of the nail. METHODS: An observational cross-sectional study with 40 patients with a diagnosis of psoriasis and without systemic treatment. The patient profile was researched, including quality of life and evaluated for the presence of psoriatic arthritis. The severity of the skin psoriasis and the presence of nail lesions were evaluated. Nail fragments were collected and analyzed through clipping. It obtained 100% of positivity for psoriasis in the histopathology exam of the nail plate. RESULTS: Of the 40 patients, 65% were diagnosed with nail psoriasis. Suggestive findings of psoriatic arthritis in hands were present in 33%, being more frequent in those with nail alteration (p = 0.01). In 92.3% of patients diagnosed with psoriatic arthritis in the hands there was some nail injury. The most frequent injuries were pitting and onycholysis. CONCLUSIONS: Patients with nail psoriasis are usually men, with worse quality of life and higher chance of psoriatic arthritis. The correlation between the nail involvement of psoriasis and psoriatic arthritis in hands confirms the association between these two forms. The clinical diagnosis of nail psoriasis did not correlate with the histological diagnosis.
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spelling pubmed-49382732016-07-11 Incidence, clinical manifestations and clipping of nail psoriasis in the dermatology center of the Hospital Universitário Evangélico de Curitiba Garbers, Luiz Eduardo Fabricio de Melo Slongo, Helena Fabricio, Lincoln Helder Zambaldi Schmitt, Juliano Vilaverde Bonalumi Filho, Aguinaldo An Bras Dermatol Investigation BACKGROUND: Psoriasis is a chronic inflammatory skin disease that often progresses with nail alterations. It is suspected that there is a correlation between nail psoriasis and enthesitis of the distal interphalangeal joint, seeming to serve as a predictor. OBJECTIVES: To analyze the profile of patients with nail psoriasis and correlate the presence of nail alterations with psoriatic arthritis, quality of life, extent of psoriasis and the histopathology of the nail. METHODS: An observational cross-sectional study with 40 patients with a diagnosis of psoriasis and without systemic treatment. The patient profile was researched, including quality of life and evaluated for the presence of psoriatic arthritis. The severity of the skin psoriasis and the presence of nail lesions were evaluated. Nail fragments were collected and analyzed through clipping. It obtained 100% of positivity for psoriasis in the histopathology exam of the nail plate. RESULTS: Of the 40 patients, 65% were diagnosed with nail psoriasis. Suggestive findings of psoriatic arthritis in hands were present in 33%, being more frequent in those with nail alteration (p = 0.01). In 92.3% of patients diagnosed with psoriatic arthritis in the hands there was some nail injury. The most frequent injuries were pitting and onycholysis. CONCLUSIONS: Patients with nail psoriasis are usually men, with worse quality of life and higher chance of psoriatic arthritis. The correlation between the nail involvement of psoriasis and psoriatic arthritis in hands confirms the association between these two forms. The clinical diagnosis of nail psoriasis did not correlate with the histological diagnosis. Sociedade Brasileira de Dermatologia 2016 /pmc/articles/PMC4938273/ /pubmed/27438196 http://dx.doi.org/10.1590/abd1806-4841.20164296 Text en © 2016 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited.
spellingShingle Investigation
Garbers, Luiz Eduardo Fabricio de Melo
Slongo, Helena
Fabricio, Lincoln Helder Zambaldi
Schmitt, Juliano Vilaverde
Bonalumi Filho, Aguinaldo
Incidence, clinical manifestations and clipping of nail psoriasis in the dermatology center of the Hospital Universitário Evangélico de Curitiba
title Incidence, clinical manifestations and clipping of nail psoriasis in the dermatology center of the Hospital Universitário Evangélico de Curitiba
title_full Incidence, clinical manifestations and clipping of nail psoriasis in the dermatology center of the Hospital Universitário Evangélico de Curitiba
title_fullStr Incidence, clinical manifestations and clipping of nail psoriasis in the dermatology center of the Hospital Universitário Evangélico de Curitiba
title_full_unstemmed Incidence, clinical manifestations and clipping of nail psoriasis in the dermatology center of the Hospital Universitário Evangélico de Curitiba
title_short Incidence, clinical manifestations and clipping of nail psoriasis in the dermatology center of the Hospital Universitário Evangélico de Curitiba
title_sort incidence, clinical manifestations and clipping of nail psoriasis in the dermatology center of the hospital universitário evangélico de curitiba
topic Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938273/
https://www.ncbi.nlm.nih.gov/pubmed/27438196
http://dx.doi.org/10.1590/abd1806-4841.20164296
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