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Type 2 leprosy reaction with Sweet's syndrome-like presentation
Leprosy is a chronic disease characterized by manifestations in the peripheral nerves and skin. The course of the disease may be interrupted by acute phenomena called reactions. This article reports a peculiar case of type 2 leprosy reaction with Sweet's syndrome-like features as the first clin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Dermatologia
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938280/ https://www.ncbi.nlm.nih.gov/pubmed/27438203 http://dx.doi.org/10.1590/abd1806-4841.20164111 |
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author | Chiaratti, Francielle Chiavelli Daxbacher, Egon Luiz Rodrigues Neumann, Antonielle Borges Faria Jeunon, Thiago |
author_facet | Chiaratti, Francielle Chiavelli Daxbacher, Egon Luiz Rodrigues Neumann, Antonielle Borges Faria Jeunon, Thiago |
author_sort | Chiaratti, Francielle Chiavelli |
collection | PubMed |
description | Leprosy is a chronic disease characterized by manifestations in the peripheral nerves and skin. The course of the disease may be interrupted by acute phenomena called reactions. This article reports a peculiar case of type 2 leprosy reaction with Sweet's syndrome-like features as the first clinical manifestation of leprosy, resulting in a delay in the diagnosis due to unusual clinical presentation. The patient had clinical and histopathological features reminiscent of Sweet's syndrome associated with clusters of vacuolated histiocytes containing acid-fast bacilli isolated or forming globi. Herein, it is discussed how to recognize type 2 leprosy reaction with Sweet's syndrome features, the differential diagnosis with type 1 leprosy reaction and the treatment options. When this kind of reaction is the first clinical presentation of leprosy, the correct diagnosis might be not suspected clinically, and established only with histopathologic evaluation. |
format | Online Article Text |
id | pubmed-4938280 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-49382802016-07-11 Type 2 leprosy reaction with Sweet's syndrome-like presentation Chiaratti, Francielle Chiavelli Daxbacher, Egon Luiz Rodrigues Neumann, Antonielle Borges Faria Jeunon, Thiago An Bras Dermatol Dermatopathology Leprosy is a chronic disease characterized by manifestations in the peripheral nerves and skin. The course of the disease may be interrupted by acute phenomena called reactions. This article reports a peculiar case of type 2 leprosy reaction with Sweet's syndrome-like features as the first clinical manifestation of leprosy, resulting in a delay in the diagnosis due to unusual clinical presentation. The patient had clinical and histopathological features reminiscent of Sweet's syndrome associated with clusters of vacuolated histiocytes containing acid-fast bacilli isolated or forming globi. Herein, it is discussed how to recognize type 2 leprosy reaction with Sweet's syndrome features, the differential diagnosis with type 1 leprosy reaction and the treatment options. When this kind of reaction is the first clinical presentation of leprosy, the correct diagnosis might be not suspected clinically, and established only with histopathologic evaluation. Sociedade Brasileira de Dermatologia 2016 /pmc/articles/PMC4938280/ /pubmed/27438203 http://dx.doi.org/10.1590/abd1806-4841.20164111 Text en © 2016 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited. |
spellingShingle | Dermatopathology Chiaratti, Francielle Chiavelli Daxbacher, Egon Luiz Rodrigues Neumann, Antonielle Borges Faria Jeunon, Thiago Type 2 leprosy reaction with Sweet's syndrome-like presentation |
title | Type 2 leprosy reaction with Sweet's syndrome-like presentation |
title_full | Type 2 leprosy reaction with Sweet's syndrome-like presentation |
title_fullStr | Type 2 leprosy reaction with Sweet's syndrome-like presentation |
title_full_unstemmed | Type 2 leprosy reaction with Sweet's syndrome-like presentation |
title_short | Type 2 leprosy reaction with Sweet's syndrome-like presentation |
title_sort | type 2 leprosy reaction with sweet's syndrome-like presentation |
topic | Dermatopathology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938280/ https://www.ncbi.nlm.nih.gov/pubmed/27438203 http://dx.doi.org/10.1590/abd1806-4841.20164111 |
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