Ulcerations due to methotrexate toxicity in a psoriasis patient

Methotrexate is one of the most used drugs in the treatment of psoriasis with indication of systemic therapy. Cutaneous and mucous side effects are described by pharmacological characteristics of the drug itself or due to overdose. We report the case of a patient with ulcerations in oral mucosa and...

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Detalles Bibliográficos
Autores principales: Souza, Claudia Fernanda Dias, Suarez, Olga Milena Zarco, da Silva, Talita Fonseca Medeiros, Gorenstein, Ana Carolina Lourenço Araújo, Quintella, Leonardo Pereira, Avelleira, João Carlos Regazzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938288/
https://www.ncbi.nlm.nih.gov/pubmed/27438211
http://dx.doi.org/10.1590/abd1806-4841.20163960
Descripción
Sumario:Methotrexate is one of the most used drugs in the treatment of psoriasis with indication of systemic therapy. Cutaneous and mucous side effects are described by pharmacological characteristics of the drug itself or due to overdose. We report the case of a patient with ulcerations in oral mucosa and psoriatic plaques after incorrect use of Methotrexate. Prescribed in a weekly dose, it was used continuously for 10 days and without simultaneous intake of folic acid. It is important to ensure correct comprehension of the prescription.

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