Ulcerations due to methotrexate toxicity in a psoriasis patient

Methotrexate is one of the most used drugs in the treatment of psoriasis with indication of systemic therapy. Cutaneous and mucous side effects are described by pharmacological characteristics of the drug itself or due to overdose. We report the case of a patient with ulcerations in oral mucosa and...

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Autores principales: Souza, Claudia Fernanda Dias, Suarez, Olga Milena Zarco, da Silva, Talita Fonseca Medeiros, Gorenstein, Ana Carolina Lourenço Araújo, Quintella, Leonardo Pereira, Avelleira, João Carlos Regazzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938288/
https://www.ncbi.nlm.nih.gov/pubmed/27438211
http://dx.doi.org/10.1590/abd1806-4841.20163960
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author Souza, Claudia Fernanda Dias
Suarez, Olga Milena Zarco
da Silva, Talita Fonseca Medeiros
Gorenstein, Ana Carolina Lourenço Araújo
Quintella, Leonardo Pereira
Avelleira, João Carlos Regazzi
author_facet Souza, Claudia Fernanda Dias
Suarez, Olga Milena Zarco
da Silva, Talita Fonseca Medeiros
Gorenstein, Ana Carolina Lourenço Araújo
Quintella, Leonardo Pereira
Avelleira, João Carlos Regazzi
author_sort Souza, Claudia Fernanda Dias
collection PubMed
description Methotrexate is one of the most used drugs in the treatment of psoriasis with indication of systemic therapy. Cutaneous and mucous side effects are described by pharmacological characteristics of the drug itself or due to overdose. We report the case of a patient with ulcerations in oral mucosa and psoriatic plaques after incorrect use of Methotrexate. Prescribed in a weekly dose, it was used continuously for 10 days and without simultaneous intake of folic acid. It is important to ensure correct comprehension of the prescription.
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spelling pubmed-49382882016-07-11 Ulcerations due to methotrexate toxicity in a psoriasis patient Souza, Claudia Fernanda Dias Suarez, Olga Milena Zarco da Silva, Talita Fonseca Medeiros Gorenstein, Ana Carolina Lourenço Araújo Quintella, Leonardo Pereira Avelleira, João Carlos Regazzi An Bras Dermatol Case Report Methotrexate is one of the most used drugs in the treatment of psoriasis with indication of systemic therapy. Cutaneous and mucous side effects are described by pharmacological characteristics of the drug itself or due to overdose. We report the case of a patient with ulcerations in oral mucosa and psoriatic plaques after incorrect use of Methotrexate. Prescribed in a weekly dose, it was used continuously for 10 days and without simultaneous intake of folic acid. It is important to ensure correct comprehension of the prescription. Sociedade Brasileira de Dermatologia 2016 /pmc/articles/PMC4938288/ /pubmed/27438211 http://dx.doi.org/10.1590/abd1806-4841.20163960 Text en © 2016 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited.
spellingShingle Case Report
Souza, Claudia Fernanda Dias
Suarez, Olga Milena Zarco
da Silva, Talita Fonseca Medeiros
Gorenstein, Ana Carolina Lourenço Araújo
Quintella, Leonardo Pereira
Avelleira, João Carlos Regazzi
Ulcerations due to methotrexate toxicity in a psoriasis patient
title Ulcerations due to methotrexate toxicity in a psoriasis patient
title_full Ulcerations due to methotrexate toxicity in a psoriasis patient
title_fullStr Ulcerations due to methotrexate toxicity in a psoriasis patient
title_full_unstemmed Ulcerations due to methotrexate toxicity in a psoriasis patient
title_short Ulcerations due to methotrexate toxicity in a psoriasis patient
title_sort ulcerations due to methotrexate toxicity in a psoriasis patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938288/
https://www.ncbi.nlm.nih.gov/pubmed/27438211
http://dx.doi.org/10.1590/abd1806-4841.20163960
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