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NLRC5 elicits antitumor immunity by enhancing processing and presentation of tumor antigens to CD8(+) T lymphocytes
Cancers can escape immunesurveillance by diminishing the expression of MHC class-I molecules (MHC-I) and components of the antigen-processing machinery (APM). Developing new approaches to reverse these defects could boost the efforts to restore antitumor immunity. Recent studies have shown that the...
Autores principales: | Rodriguez, Galaxia M., Bobbala, Diwakar, Serrano, Daniel, Mayhue, Marian, Champagne, Audrey, Saucier, Caroline, Steimle, Viktor, Kufer, Thomas A., Menendez, Alfredo, Ramanathan, Sheela, Ilangumaran, Subburaj |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938303/ https://www.ncbi.nlm.nih.gov/pubmed/27471621 http://dx.doi.org/10.1080/2162402X.2016.1151593 |
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