DC vaccine generated by ALA-PDT-induced immunogenic apoptotic cells for skin squamous cell carcinoma

Dendritic cell (DC) vaccines were generated by apoptotic squamous cell carcinoma (SCC) cells induced by 5-aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT). ALA-PDT-DC vaccine inhibited the growth of SCC in mice, indicating that immunogenic apoptotic cells can activate an effective antit...

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Detalles Bibliográficos
Autores principales: Ji, Jie, Zhang, Yunfeng, Chen, Wei R., Wang, Xiuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938317/
https://www.ncbi.nlm.nih.gov/pubmed/27471605
http://dx.doi.org/10.1080/2162402X.2015.1072674
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author Ji, Jie
Zhang, Yunfeng
Chen, Wei R.
Wang, Xiuli
author_facet Ji, Jie
Zhang, Yunfeng
Chen, Wei R.
Wang, Xiuli
author_sort Ji, Jie
collection PubMed
description Dendritic cell (DC) vaccines were generated by apoptotic squamous cell carcinoma (SCC) cells induced by 5-aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT). ALA-PDT-DC vaccine inhibited the growth of SCC in mice, indicating that immunogenic apoptotic cells can activate an effective antitumor adaptive immunity and lead to a DC vaccine-based cancer immunotherapy.
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spelling pubmed-49383172016-07-28 DC vaccine generated by ALA-PDT-induced immunogenic apoptotic cells for skin squamous cell carcinoma Ji, Jie Zhang, Yunfeng Chen, Wei R. Wang, Xiuli Oncoimmunology Author's View Dendritic cell (DC) vaccines were generated by apoptotic squamous cell carcinoma (SCC) cells induced by 5-aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT). ALA-PDT-DC vaccine inhibited the growth of SCC in mice, indicating that immunogenic apoptotic cells can activate an effective antitumor adaptive immunity and lead to a DC vaccine-based cancer immunotherapy. Taylor & Francis 2015-08-31 /pmc/articles/PMC4938317/ /pubmed/27471605 http://dx.doi.org/10.1080/2162402X.2015.1072674 Text en © 2016 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0/, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Ji, Jie
Zhang, Yunfeng
Chen, Wei R.
Wang, Xiuli
DC vaccine generated by ALA-PDT-induced immunogenic apoptotic cells for skin squamous cell carcinoma
title DC vaccine generated by ALA-PDT-induced immunogenic apoptotic cells for skin squamous cell carcinoma
title_full DC vaccine generated by ALA-PDT-induced immunogenic apoptotic cells for skin squamous cell carcinoma
title_fullStr DC vaccine generated by ALA-PDT-induced immunogenic apoptotic cells for skin squamous cell carcinoma
title_full_unstemmed DC vaccine generated by ALA-PDT-induced immunogenic apoptotic cells for skin squamous cell carcinoma
title_short DC vaccine generated by ALA-PDT-induced immunogenic apoptotic cells for skin squamous cell carcinoma
title_sort dc vaccine generated by ala-pdt-induced immunogenic apoptotic cells for skin squamous cell carcinoma
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938317/
https://www.ncbi.nlm.nih.gov/pubmed/27471605
http://dx.doi.org/10.1080/2162402X.2015.1072674
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AT chenweir dcvaccinegeneratedbyalapdtinducedimmunogenicapoptoticcellsforskinsquamouscellcarcinoma
AT wangxiuli dcvaccinegeneratedbyalapdtinducedimmunogenicapoptoticcellsforskinsquamouscellcarcinoma

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