Ampelopsin Improves Insulin Resistance by Activating PPARγ and Subsequently Up-Regulating FGF21-AMPK Signaling Pathway

Ampelopsin (APL), a major bioactive constituent of Ampelopsis grossedentata, exerts a number of biological effects. Here, we explored the anti-diabetic activity of APL and elucidate the underlying mechanism of this action. In palmitate-induced insulin resistance of L6 myotubes, APL treatment markedl...

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Detalles Bibliográficos
Autores principales: Zhou, Yong, Wu, Ying, Qin, Yu, Liu, Lei, Wan, Jing, Zou, Lingyun, Zhang, Qianyong, Zhu, Jundong, Mi, Mantian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938387/
https://www.ncbi.nlm.nih.gov/pubmed/27391974
http://dx.doi.org/10.1371/journal.pone.0159191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938387/
https://www.ncbi.nlm.nih.gov/pubmed/27391974
http://dx.doi.org/10.1371/journal.pone.0159191

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