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Ampelopsin Improves Insulin Resistance by Activating PPARγ and Subsequently Up-Regulating FGF21-AMPK Signaling Pathway
Ampelopsin (APL), a major bioactive constituent of Ampelopsis grossedentata, exerts a number of biological effects. Here, we explored the anti-diabetic activity of APL and elucidate the underlying mechanism of this action. In palmitate-induced insulin resistance of L6 myotubes, APL treatment markedl...
Autores principales: | Zhou, Yong, Wu, Ying, Qin, Yu, Liu, Lei, Wan, Jing, Zou, Lingyun, Zhang, Qianyong, Zhu, Jundong, Mi, Mantian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938387/ https://www.ncbi.nlm.nih.gov/pubmed/27391974 http://dx.doi.org/10.1371/journal.pone.0159191 |
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