Reduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated with Activation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of Essential Hypertension

The proliferation of vascular smooth muscle cells (VSMCs), remodeling of the vasculature, and the renin-angiotensin system (RAS) play important roles in the development of essential hypertension (EH), which is defined as high blood pressure (BP) in which secondary causes, such as renovascular diseas...

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Detalles Bibliográficos
Autores principales: Qu, Yuan-yuan, Hui, Jing, Wang, La-mei, Tang, Na, Zhong, Hua, Liu, Yong-min, Li, Zhen, Feng, Qian, He, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938397/
https://www.ncbi.nlm.nih.gov/pubmed/27391973
http://dx.doi.org/10.1371/journal.pone.0157456

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