Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington’s Disease

Recent systems-based analyses have demonstrated that sleep and stress traits emerge from shared genetic and transcriptional networks, and clinical work has elucidated the emergence of sleep dysfunction and stress susceptibility as early symptoms of Huntington's disease. Understanding the biolog...

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Detalles Bibliográficos
Autores principales: Scarpa, Joseph R., Jiang, Peng, Losic, Bojan, Readhead, Ben, Gao, Vance D., Dudley, Joel T., Vitaterna, Martha H., Turek, Fred W., Kasarskis, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938493/
https://www.ncbi.nlm.nih.gov/pubmed/27390852
http://dx.doi.org/10.1371/journal.pgen.1006137

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