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Autophagy and Mitochondrial Dysfunction in Tenon Fibroblasts from Exfoliation Glaucoma Patients

PURPOSE: To test the hypothesis that autophagy dysfunction is involved in exfoliation syndrome (XFS), a systemic disorder of extracellular elastic matrices that causes a distinct form of human glaucoma. METHODS: Fibroblasts derived from tenon tissue discards (TFs) from filtration surgery to relieve...

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Detalles Bibliográficos
Autores principales:	Want, Andrew, Gillespie, Stephanie R., Wang, Zheng, Gordon, Ronald, Iomini, Carlo, Ritch, Robert, Wolosin, J. Mario, Bernstein, Audrey M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938507/ https://www.ncbi.nlm.nih.gov/pubmed/27391778 http://dx.doi.org/10.1371/journal.pone.0157404

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