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Functional Importance of a Proteoglycan Coreceptor in Pathologic Lymphangiogenesis

RATIONALE: Lymphatic vessel growth is mediated by major prolymphangiogenic factors, such as vascular endothelial growth factor (VEGF-C) and VEGF-D, among other endothelial effectors. Heparan sulfate is a linear polysaccharide expressed on proteoglycan core proteins on cell membranes and matrix, play...

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Detalles Bibliográficos
Autores principales: Johns, Scott C., Yin, Xin, Jeltsch, Michael, Bishop, Joseph R., Schuksz, Manuela, El Ghazal, Roland, Wilcox-Adelman, Sarah A., Alitalo, Kari, Fuster, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938725/
https://www.ncbi.nlm.nih.gov/pubmed/27225479
http://dx.doi.org/10.1161/CIRCRESAHA.116.308504

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