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Physiologically Based Pharmacokinetic (PBPK) Model for Biodistribution of Radiolabeled Peptides in Patients with Neuroendocrine Tumours

OBJECTIVE(S): The objectives of this work was to assess the benefits of the application of Physiologically Based Pharmacokinetic (PBPK) models in patients with different neuroendocrine tumours (NET) who were treated with Lu-177 DOTATATE. The model utilises clinical data on biodistribution of radiola...

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Detalles Bibliográficos
Autores principales: Gospavic, Radovan, Knoll, Peter, Mirzaei, Siroos, Popov, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asia Oceania Journal of Nuclear Medicine & Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938879/
https://www.ncbi.nlm.nih.gov/pubmed/27408897
http://dx.doi.org/10.7508/aojnmb.2016.02.005