Antibodies to the RNA-binding protein hnRNP A1 contribute to neurodegeneration in a model of central nervous system autoimmune inflammatory disease

BACKGROUND: Neurodegeneration is believed to be the primary cause of permanent, long-term disability in patients with multiple sclerosis. The cause of neurodegeneration in multiple sclerosis appears to be multifactorial. One mechanism that has been implicated in the pathogenesis of neurodegeneration...

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Detalles Bibliográficos
Autores principales: Douglas, Joshua N., Gardner, Lidia A., Salapa, Hannah E., Lalor, Stephen J., Lee, Sangmin, Segal, Benjamin M., Sawchenko, Paul E., Levin, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938923/
https://www.ncbi.nlm.nih.gov/pubmed/27391474
http://dx.doi.org/10.1186/s12974-016-0647-y

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