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Structural effects of sprifermin in knee osteoarthritis: a post-hoc analysis on cartilage and non-cartilaginous tissue alterations in a randomized controlled trial

BACKGROUND: A recent publication on efficacy of Sprifermin for knee osteoarthritis (OA) using quantitatively MRI-defined central medial tibio-femoral compartment cartilage thickness as the structural primary endpoint reported no statistically significant dose response. However, Sprifermin was associ...

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Detalles Bibliográficos
Autores principales:	Roemer, Frank W., Aydemir, Aida, Lohmander, Stefan, Crema, Michel D., Marra, Monica Dias, Muurahainen, Norma, Felson, David T., Eckstein, Felix, Guermazi, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938999/ https://www.ncbi.nlm.nih.gov/pubmed/27393009 http://dx.doi.org/10.1186/s12891-016-1128-2

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