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Chromatin variation associated with liver metabolism is mediated by transposable elements

BACKGROUND: Functional regulatory regions in eukaryotic genomes are characterized by the disruption of nucleosomes leading to accessible chromatin. The modulation of chromatin accessibility is one of the key mediators of transcriptional regulation, and variation in chromatin accessibility across ind...

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Detalles Bibliográficos
Autores principales:	Du, Juan, Leung, Amy, Trac, Candi, Lee, Michael, Parks, Brian W., Lusis, Aldons J., Natarajan, Rama, Schones, Dustin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939004/ https://www.ncbi.nlm.nih.gov/pubmed/27398095 http://dx.doi.org/10.1186/s13072-016-0078-0

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