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Overexpression of membrane-bound gluconate-2-dehydrogenase to enhance the production of 2-keto-d-gluconic acid by Gluconobacter oxydans

BACKGROUND: 2-keto-d-gluconic acid (2KGA) is widely used as a chemical intermediate in the cosmetic, pharmaceutical and environmental industries. Several microbial fermentation processes have been developed for production of 2KGA but these suffer from substrate/product inhibition, byproduct formatio...

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Detalles Bibliográficos
Autores principales: Li, Kefei, Mao, Xinlei, Liu, Liu, Lin, Jinping, Sun, Ming, Wei, Dongzhi, Yang, Shengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939059/
https://www.ncbi.nlm.nih.gov/pubmed/27392695
http://dx.doi.org/10.1186/s12934-016-0521-8