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Direct observation of DNA threading in flap endonuclease complexes

Maintenance of genome integrity requires that branched nucleic acid molecules are accurately processed to produce double-helical DNA. Flap endonucleases are essential enzymes that trim such branched molecules generated by Okazaki fragment synthesis during replication. Here, we report crystal structu...

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Detalles Bibliográficos
Autores principales:	AlMalki, Faizah A, Flemming, Claudia S, Zhang, Jing, Feng, Min, Sedelnikova, Svetlana E, Ceska, Tom, Rafferty, John B, Sayers, Jon R, Artymiuk, Peter J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939078/ https://www.ncbi.nlm.nih.gov/pubmed/27273516 http://dx.doi.org/10.1038/nsmb.3241

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