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Study of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT(6) partial agonist in rats
It was shown that 5-HT(6) receptor agonists can exert pharmacological activity due to various modifications in monoamines’ level and metabolism activity in rats’ brain structures. This finding was correlated with antidepressant- or anxiolytic-like properties of these compounds. The study was designe...
Autores principales: | Jastrzębska-Więsek, Magdalena, Siwek, Agata, Partyka, Anna, Antkiewicz-Michaluk, Lucyna, Michaluk, Jerzy, Romańska, Irena, Kołaczkowski, Marcin, Wesołowska, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939156/ https://www.ncbi.nlm.nih.gov/pubmed/27106213 http://dx.doi.org/10.1007/s00210-016-1245-3 |
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