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Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's Disease

The failure of several Phase II/III clinical trials in Alzheimer's disease (AD) with drugs targeting β-amyloid accumulation in the brain fuelled an increasing interest in alternative treatments against tau pathology, including approaches targeting tau phosphatases/kinases, active and passive im...

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Detalles Bibliográficos
Autores principales: Panza, Francesco, Solfrizzi, Vincenzo, Seripa, Davide, Imbimbo, Bruno P., Lozupone, Madia, Santamato, Andrea, Zecca, Chiara, Barulli, Maria Rosaria, Bellomo, Antonello, Pilotto, Alberto, Daniele, Antonio, Greco, Antonio, Logroscino, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939203/
https://www.ncbi.nlm.nih.gov/pubmed/27429978
http://dx.doi.org/10.1155/2016/3245935